Hye! I am trying to elucidate the role of Autophagy proteins in MSCs survival and death in ischemic stroke. My initial studies suggest that Autophagy plays a crucial role in cell survival and death. Further I am interested in exploring the crosstalk involved between these proteins.
Achievements: Ph.D. (CDRI-JNU), CSIR-UGC JRF Dec. 2010, June 2009, GATE’2010 (AIR 301)
Hi! Myself Dinesh Kr. Verma (Ph.D. CDRI-JNU) and here I am trying to explore the mechanisms of NLRP3 inflammasome activation implicated in inflammatory diseases e.g.- stroke (in vivo and in vitro) and alzheimer's disease (in vivo). To explore the mechanism of afore-mentioned inflammasomal pathway, I am employing novel molecules (like MCC950) which is a specific inhibitor of NLRP3-inflammasome.
Achievements: CSIR–UGC NET (JRF) Dec’2010 and GATE’2011
I am Nidhi Sachan, I have joined Dr. Shadab’s lab in January, 2017 and I am interested in pursuing my Ph.D. in stem cell therapy in brain injury recovery. My present project involves NLRP3 Inflammasome activation in ischemic stroke, and its inhibition through novel chemical compounds. For the mentioned project, I am employing both mouse and human stem cells along with a couple of inflammasome inhibitors.
Achievements: M.Sc. Gold Medalist, CSIR-NET'2016 (AIR 74), Gate'2015 (AIR 1089)
I am a M. Pharm student from Babu Banarasi Das University, Lucknow, working at Dr. Shadab's lab for my M.Pharm thesis on a research project entitled "Almunium chloride induced neuroinflammation negatively affects adult hippocampus neurogenesis in aged mice". My hobbies are reading, playing chess, curiosity to know new thing.
Hi, I am an ICMR sponsored Project Fellow’ 2017, working on a project entitled "Activation of NLRP3 inflammasome regulate the fate of human MSCs”.